Immunotherapy in Head and Neck Squamous Cell Cancer
نویسندگان
چکیده
منابع مشابه
human papilloma virus in head and neck squamous cell cancer
background: epidemiologic and molecular evidences have established a strong link between high risk types of human papilloma virus and a subgroup of head and neck squamous cell carcinomas (hnscc). we evaluated the frequency of hpv positivity in hnscc and its relationship to demographic and some risk factor variables in an open case- control study. methods: fourteen recently diagnosed patients wi...
متن کاملImmunotherapy for head and neck squamous cell carcinoma
Over the past years immuno-oncology has evolved and become a novel promising strategy for cancer therapy. Immune checkpoint inhibitors such as pembrolizumab or nivolumab, which target the interaction between programmed death receptor 1/programmed death ligand 1 (PD-1/PDL-1) and PDL-2, have been recently approved for the treatment of various malignancies and are currently being investigated in c...
متن کاملImmunotherapy for Head and Neck Squamous Cell Carcinoma
PURPOSE OF REVIEW Discussion of current strategies targeting the immune system related to solid tumors with emphasis on head and neck squamous cell carcinoma (HNSCC).This review will outline the current challenges with immunotherapy and future goals for treatment using these agents. RECENT FINDINGS Agents targeting immune checkpoint receptors (IR) such as program death 1 (PD1) have been used ...
متن کاملHead and neck cancer (squamous cell)
Squamous cell carcinoma of the head and neck (SCCHN) is the fifth most common neoplasm worldwide, with an estimated global incidence of more than 500,000 cases per annum (1). The UK incidence was 7745 cases per year in 2006 (2). SCCHN presents formidable challenges for therapeutic intervention and these are often secondary to the vulnerability of critical anatomical structures in the head and n...
متن کاملNovel neoadjuvant immunotherapy regimen safety and survival in head and neck squamous cell cancer.
BACKGROUND Cellular immune suppression is observed in head and neck squamous cell cancer (HNSCC) and contributes to poor prognosis. Restoration of immune homeostasis may require primary cell-derived cytokines at physiologic doses. An immunotherapy regimen containing a biologic, with multiple-active cytokine components, and administered with cytoxan, zinc, and indomethacin was developed to modul...
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ژورنال
عنوان ژورنال: Clinical and Experimental Otorhinolaryngology
سال: 2018
ISSN: 1976-8710,2005-0720
DOI: 10.21053/ceo.2018.00150